Ohio State Racing Commission has removed the therapeutic medication, isoxsuprine from the OSRC Therapeutic Substance List effective September 1, 2022. The FDA withdrew approval and the Association of Racing Commissioners International established isoxsuprine as a non-approved substance. Being non-approved results in a violation at the level of detection. The updated OSRC Therapeutic Substance list is here. Note, isoxsuprine can be detected in post-race samples for a variable time period, if in use consult with your racetrack veterinarian for guidance on out-time for the September 1st effective date.